GenEng News  Aug 16  Comment 
It may be a caricature, but it is recognized by ailing blood vessels, which respond by moving closer to a picture of cardiovascular health. The “it” is an artificial protein called ApoM-Fc that mimics apolipoprotein M (ApoM), a natural protein...
GenEng News  Aug 14  Comment 
Researchers at the Cedars-Sinai Heart Institute have shown that injecting cardiac stem cells from young rats into the hearts of old rats can help to reverse the natural cardiac aging process. Results from the studies, led by Eduardo Marbán, M.D.,...
MedPage Today  Aug 11  Comment 
(MedPage Today) -- Cardiovascular Daily wraps up the top cardiology news of the week
Forbes  Aug 10  Comment 
Color Genomics, a Burlingame, Calif.-based startup that made a name for itself selling tests for genes that dramatically raise the risk of cancer, is moving into heart disease. In doing so, it is stepping more deeply into the continuing debate...
The Hindu Business Line  Aug 9  Comment 
Drug firm Lupin has received approval from the US health regulator to market Pitavastatin tablets used for lowering cholesterol. In a BSE filing, Lupin said it has received 505 (b) (2) NDA approval...
Motley Fool  Aug 8  Comment 
Positive top-line results for Esperion's lead candidate are giving investors a reason to cheer.
GenEng News  Aug 8  Comment 
They say that hope deferred makes the heart sick. Well, those that have suffered heart attacks just got some good news that may afford them some new optimism and lead toward improved cardiac health. A team of investigators from The Ottawa...
FierceBiotech  Aug 7  Comment 
MyoKardia just announced that its experimental drug mavacamten improved heart function in patients with an inherited cardiac condition, with eight of 10 showing normal readings after treatment with the drug.
FierceBiotech  Aug 7  Comment 
Gemphire Therapeutics has posted data on its oral inhibitor of cholesterol production. The phase 2b met its primary endpoint but also linked gemcabene to a smaller-than-hoped drop in LDL cholesterol, raising doubts about the commercial viability...



In modern times, cardiac disease has emerged as the leading cause of death worldwide, particularly in developed countries. The World Health Organization reported that 16.7 million deaths in 2003 (29.2% of total global deaths) were caused by some form of cardiovascular disease. Though the rate of cardiac disease is highest in developed countries, developing countries are seeing an increase in the occurrence of cardiac disease, as well as a corresponding rise in the number of heart-related deaths. The World Health Organization estimates that by 2010, cardiac disease will surpass AIDS as the leading cause of death in developing countries.

As the largest cause of death worldwide, cardiac disease has spawned the development of an entire industry dedicated to its treatment. T

What is cardiac disease?

Cardiac (or cardiovascular) disease refers to any condition affecting the ability of the heart and/or blood vessels to function properly. There are many different kinds of cardiac disease, but they all threaten the circulatory system in one way or another. This is what makes cardiac disease so deadly; a disruption of the blood supply to any part of the body can lead to tissue damage or death, often within a matter of minutes. Some of the major types of cardiac disease include:

  • Coronary heart disease
    • CHD is the condition that results from the buildup of plaques within the walls of arteries that supply the heart muscle with oxygen and nutrients. CHD can lead to heart attacks, which occur when the buildup suddenly interrupts the heart's supply of blood, leading to the damage or death of heart tissue. This is the single largest cause of death in the world.
  • Cerebrovascular disease
    • Cerebrovascular disease is a condition in which the arteries leading the to the brain become obstructed, which can decrease blood supply to the brain. A stroke occurs when one of these arteries becomes completely blocked, cutting off the blood supply to all or part of the brain. This can result in significant brain damage, depending on the size of the obstructed artery and the duration of the blockage.
  • Hypertensive heart disease
    • Hypertension, also known as high blood pressure, can increase the risk for a number of other heart-related conditions, including heart attack, stroke, cardiac arrest, and congestive heart failure.

What causes cardiac disease?

Common risk factors are:

  • Tobacco smoking
  • High cholesterol levels
  • Obesity
  • Physical inactivity
  • Diets high in fat, salt, or refined carbohydrates
  • Elevated heart rate - can be caused by abuse of stimulant drugs


There are many drugs available for the treatment of cardiac disease. Surgery is often used to decrease the risk of cardiac arrest, heart attacks, etc. Exercise regimens and dietary modifications are commonly recommended to patients in order to combat blood cholesterol and hypertension levels.

Which companies are involved in the treatment of cardiac disease?

Pharmaceutical companies

Medical device manufacturers

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