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Affymetrix to Webcast Annual Meeting of Shareholders

Affymetrix, Inc. (Nasdaq:AFFX) today invited investors and interested parties to hear a live webcast of its Annual Shareholder Meeting at 8:00am PT on Friday, May 11th, 2012. Following the formal business of the meeting, Affymetrix President and Chief Executive Officer Frank Witney will provide an update on the company’s strategic direction and operating results.

Attendee URL:

https://www.livemeeting.com/cc/affymetrix_pro/join?id=D33DJ8&role=attend&pw=rkG%2C9.M

Participant Dial-In Number(s):

* (877) 297-7536

*Direct Event International Dial-In Number: (706) 643-6392

* Passcode: 5139525

FIRST-TIME USERS

To save time before the meeting, check your system to make sure it is ready to use Microsoft Office Live Meeting.

http://go.microsoft.com/fwlink/?LinkId=90703

A replay of the presentation will be available at http://www.affymetrix.com under the "Investors" link in the "About Affymetrix" drop-down menu. Please log in ten minutes prior to register for the webcast and check your system for the appropriate webcast software. Archived webcasts will be available for 30 days.

About Affymetrix

Affymetrix technology is used by the world's top pharmaceutical, diagnostic, and biotechnology companies, as well as leading academic, government, and nonprofit research institutes. More than 2,100 systems have been shipped around the world and over 26,000 peer-reviewed papers have been published using the technology. Affymetrix is headquartered in Santa Clara, California, and has manufacturing facilities in Cleveland, Ohio, and Singapore. The Company has more than 900 employees worldwide and maintains sales and distribution operations across Europe, Asia and Latin America. For more information about Affymetrix, please visit the Company's website.

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