LLY » Topics » EXECUTIVE OVERVIEW

This excerpt taken from the LLY 10-K filed Feb 22, 2010.
EXECUTIVE OVERVIEW
This section provides an overview of our financial results, recent product and late-stage pipeline developments, significant business development, and legal, regulatory, and other matters affecting our company and the pharmaceutical industry.
 
These excerpts taken from the LLY 10-K filed Feb 27, 2009.
EXECUTIVE OVERVIEW
 
This section provides an overview of our financial results, recent product and late-stage pipeline developments, significant business development, and legal, regulatory, and other matters affecting our company and the pharmaceutical industry.
 
Financial Results
 
We achieved worldwide sales growth of 9 percent, which was primarily driven by volume increases in several key products. The favorable impact of foreign exchange rates on cost of sales contributed to an improvement in gross margin. Marketing, selling, and administrative expenses grew at the same rate as sales, driven by pre-launch activities associated with prasugrel, marketing costs associated with Cymbalta and Evista, the impact of foreign exchange rates, and increased litigation-related expenses; while our investment in research and development grew 10 percent. We completed our acquisition of ImClone Systems Inc. (ImClone), resulting in a significant charge of $4.69 billion for acquired in-process research and development (IPR&D) and reached resolution on government investigations related to our past U.S. marketing and promotional practices for Zyprexa, resulting in an additional charge of $1.48 billion. We incurred tax expense of $764.3 million, despite a loss before income taxes of $1.31 billion, primarily caused by the non-deductibility of the ImClone IPR&D charge and the partial deductibility of the Zyprexa investigation settlements. Accordingly, earnings decreased $5.02 billion, to a net loss of $2.07 billion, and earnings per share decreased $4.60, to a loss of $1.89 per share, in 2008 as compared with net income of $2.95 billion, or earnings per share of $2.71 in 2007. Net income comparisons between 2008 and 2007 are affected by the impact of the following significant items (see Notes 3, 5, 12, and 14 to the consolidated financial statements for additional information):
 
2008
 
Acquisitions (Note 3)
 
•  We recognized charges totaling $4.73 billion (pretax) associated with the acquisition of ImClone, which decreased earnings per share by $4.46. These amounts include an IPR&D charge of $4.69 billion (pretax). The remaining net expenses are related to ImClone’s operating results subsequent to the acquisition, incremental interest costs, and amortization of the intangible asset associated with Erbitux. We also incurred IPR&D charges of $28.0 million (pretax) associated with the acquisition of SGX Pharmaceuticals, Inc. (SGX), which decreased earnings per share by $.03.
 
•  We incurred IPR&D charges associated with licensing arrangements with BioMS Medical Corp. (BioMS) and TransPharma Medical Ltd. totaling $122.0 million (pretax), which decreased earnings per share by $.07.
 


-19-


 

(CHART)
 
Asset Impairments and Related Restructuring and Other Special Charges (Notes 5 and 14)
 
•  We recognized asset impairments, restructuring, and other special charges totaling $497.0 million (pretax), which decreased earnings per share by $.30. A similar charge of $57.1 million (pretax), which decreased earnings per share by $.04, was included in cost of sales. These charges were primarily associated with the sale of our Greenfield, Indiana site, the termination of the AIR® Insulin program, and strategic exit activities related to manufacturing operations.
 
•  We recorded charges of $1.48 billion (pretax) related to the federal and state Zyprexa investigations led by the U.S. Attorney for the Eastern District of Pennsylvania (EDPA), as well as the resolution of a multi-state investigation regarding Zyprexa involving 32 states and the District of Columbia, which decreased earnings per share by $1.20.
 
Other (Note 12)
 
•  We recognized a discrete income tax benefit of $210.3 million as a result of the resolution of a substantial portion of the IRS audit of our federal income tax returns for the years 2001 through 2004, which increased earnings per share by $.19.
 
2007
 
Acquisitions (Note 3)
 
•  We incurred IPR&D charges associated with the acquisitions of ICOS Corporation (ICOS), Hypnion, Inc. (Hypnion), and Ivy Animal Health, Inc. (Ivy), totaling $631.6 million (pretax), which decreased earnings per share by $.57.
 
•  We incurred IPR&D charges associated with our licensing arrangements with Glenmark Pharmaceuticals Limited India, MacroGenics, Inc., and OSI Pharmaceuticals, totaling $114.0 million (pretax), which decreased earnings per share by $.06.

-20-


 

 
Asset Impairments and Related Restructuring and Other Special Charges (Notes 5 and 14)
 
•  We recognized asset impairments, restructuring, and other special charges of $190.6 million (pretax), which decreased earnings per share by $.12. These charges were primarily associated with previously announced strategic decisions affecting manufacturing and research facilities.
 
•  We incurred a special charge following a settlement with one of our insurance carriers over Zyprexa product liability claims, which led to a reduction of our expected product liability insurance recoveries, and other product liability charges. This resulted in a charge totaling $111.9 million (pretax), which decreased earnings per share by $.09.
 
Late-Stage Pipeline Developments and Business Development Activity
 
Our long-term success depends, to a great extent, on our ability to continue to discover and develop innovative pharmaceutical products and acquire or collaborate on compounds currently in development by other biotech-nology or pharmaceutical companies. There were a number of late-stage pipeline developments and business development transactions within the past year, including:
 
EXECUTIVE
OVERVIEW



 



This section provides an overview of our financial results,
recent product and late-stage pipeline developments, significant
business development, and legal, regulatory, and other matters
affecting our company and the pharmaceutical industry.


 




Financial
Results



 



We achieved worldwide sales growth of 9 percent, which was
primarily driven by volume increases in several key products.
The favorable impact of foreign exchange rates on cost of sales
contributed to an improvement in gross margin. Marketing,
selling, and administrative expenses grew at the same rate as
sales, driven by pre-launch activities associated with
prasugrel, marketing costs associated with Cymbalta and Evista,
the impact of foreign exchange rates, and increased
litigation-related expenses; while our investment in research
and development grew 10 percent. We completed our
acquisition of ImClone Systems Inc. (ImClone), resulting in a
significant charge of $4.69 billion for acquired in-process
research and development (IPR&D) and reached resolution on
government investigations related to our past
U.S. marketing and promotional practices for Zyprexa,
resulting in an additional charge of $1.48 billion. We
incurred tax expense of $764.3 million, despite a loss
before income taxes of $1.31 billion, primarily caused by
the non-deductibility of the ImClone IPR&D charge and the
partial deductibility of the Zyprexa investigation settlements.
Accordingly, earnings decreased $5.02 billion, to a net
loss of $2.07 billion, and earnings per share decreased
$4.60, to a loss of $1.89 per share, in 2008 as compared with
net income of $2.95 billion, or earnings per share of $2.71
in 2007. Net income comparisons between 2008 and 2007 are
affected by the impact of the following significant items (see
Notes 3, 5, 12, and 14 to the consolidated financial
statements for additional information):


 




2008


 




Acquisitions
(Note 3)



 























• 
We recognized charges totaling $4.73 billion (pretax)
associated with the acquisition of ImClone, which decreased
earnings per share by $4.46. These amounts include an IPR&D
charge of $4.69 billion (pretax). The remaining net
expenses are related to ImClone’s operating results
subsequent to the acquisition, incremental interest costs, and
amortization of the intangible asset associated with Erbitux. We
also incurred IPR&D charges of $28.0 million (pretax)
associated with the acquisition of SGX Pharmaceuticals, Inc.
(SGX), which decreased earnings per share by $.03.
 
• 
We incurred IPR&D charges associated with licensing
arrangements with BioMS Medical Corp. (BioMS) and TransPharma
Medical Ltd. totaling $122.0 million (pretax), which
decreased earnings per share by $.07.


 





-19-





 






(CHART)


 



Asset Impairments and Related Restructuring and Other
Special Charges (Notes 5 and 14)



 























• 
We recognized asset impairments, restructuring, and other
special charges totaling $497.0 million (pretax), which
decreased earnings per share by $.30. A similar charge of
$57.1 million (pretax), which decreased earnings per share
by $.04, was included in cost of sales. These charges were
primarily associated with the sale of our Greenfield, Indiana
site, the termination of the
AIR®

Insulin program, and strategic exit activities related to
manufacturing operations.
 
• 
We recorded charges of $1.48 billion (pretax) related to
the federal and state Zyprexa investigations led by the
U.S. Attorney for the Eastern District of Pennsylvania
(EDPA), as well as the resolution of a multi-state investigation
regarding Zyprexa involving 32 states and the District of
Columbia, which decreased earnings per share by $1.20.


 




Other
(Note 12)



 














• 
We recognized a discrete income tax benefit of
$210.3 million as a result of the resolution of a
substantial portion of the IRS audit of our federal income tax
returns for the years 2001 through 2004, which increased
earnings per share by $.19.


 




2007


 




Acquisitions
(Note 3)



 























• 
We incurred IPR&D charges associated with the acquisitions
of ICOS Corporation (ICOS), Hypnion, Inc. (Hypnion), and
Ivy Animal Health, Inc. (Ivy), totaling $631.6 million
(pretax), which decreased earnings per share by $.57.
 
• 
We incurred IPR&D charges associated with our licensing
arrangements with Glenmark Pharmaceuticals Limited India,
MacroGenics, Inc., and OSI Pharmaceuticals, totaling
$114.0 million (pretax), which decreased earnings per share
by $.06.



-20-





 





 




Asset
Impairments and Related Restructuring and Other Special Charges
(Notes 5 and 14)



 























• 
We recognized asset impairments, restructuring, and other
special charges of $190.6 million (pretax), which decreased
earnings per share by $.12. These charges were primarily
associated with previously announced strategic decisions
affecting manufacturing and research facilities.
 
• 
We incurred a special charge following a settlement with one of
our insurance carriers over Zyprexa product liability claims,
which led to a reduction of our expected product liability
insurance recoveries, and other product liability charges. This
resulted in a charge totaling $111.9 million (pretax),
which decreased earnings per share by $.09.


 




Late-Stage
Pipeline Developments and Business Development
Activity



 



Our long-term success depends, to a great extent, on our ability
to continue to discover and develop innovative pharmaceutical
products and acquire or collaborate on compounds currently in
development by other biotech-nology or pharmaceutical companies.
There were a number of late-stage pipeline developments and
business development transactions within the past year,
including:


 




These excerpts taken from the LLY 10-K filed Oct 21, 2008.
EXECUTIVE OVERVIEW
 
This section provides an overview of our financial results, significant business development, recent product and late-stage pipeline developments, and legal, regulatory, and other matters affecting our company and the pharmaceutical industry.
 
Financial Results
 
We achieved worldwide sales growth of 19 percent. This growth was primarily driven by volume increases in a number of key products, with a significant portion of this increase in volume resulting from the acquisition of ICOS. Our additional investments in marketing and selling expenses in support of key products, primarily Cymbalta® and the diabetes care products, contributed to this sales growth and enabled us to increase our investment in research and development 11 percent in 2007. While cost of sales and operating expenses in the aggregate grew at approximately the same rate as sales, other income — net decreased and the effective tax rate increased. As a result, net income and earnings per share increased 11 percent, to $2.95 billion, or $2.71 per share, in 2007 as compared with $2.66 billion, or $2.45 per share, in 2006. Net income comparisons between 2007 and 2006 are affected by the impact of the following significant items that are reflected in our financial results (see Notes 4, 5, and 14 to the consolidated financial statements for additional information):
 
2007
 
•  We recognized asset impairments, restructuring, and other special charges of $98.2 million (pretax) in the fourth quarter, which decreased earnings per share by $.07. In the first quarter, we recognized similar charges associated with previously announced strategic decisions affecting manufacturing and research facilities of $123.0 million (pretax), which decreased earnings per share by $.08 (Note 5).
 
•  We incurred a special charge following a settlement with one of our insurance carriers over Zyprexa® product liability claims, which led to a reduction of our expected product liability insurance recoveries. This resulted in a charge of $81.3 million (pretax), which decreased earnings per share by $.06 in the third quarter (Notes 5 and 14).
 
•  We incurred in-process research and development (IPR&D) charges associated with our licensing arrangement with Glenmark Pharmaceuticals Limited India of $45.0 million (pretax) and our licensing arrangement with MacroGenics, Inc., of $44.0 million (pretax), which decreased earnings per share by $.05 in the fourth quarter (Note 4).


-17-


Table of Contents

 
•  We incurred IPR&D charges associated with the acquisition of Hypnion, Inc. (Hypnion), of $291.1 million (no tax benefit) and the acquisition of Ivy Animal Health, Inc. (Ivy), of $37.0 million (pretax), which decreased earnings per share by $.29 in the second quarter (Note 4).
 
•  We incurred IPR&D charges associated with the acquisition of ICOS of $303.5 million (no tax benefit) and a licensing arrangement with OSI Pharmaceuticals of $25.0 million (pretax), which decreased earnings per share by $.29 in the first quarter (Note 4).
 
2006
 
•  We recognized asset impairments, restructuring, and other special charges of $450.3 million (pretax) in the fourth quarter, which decreased earnings per share by $.31 (Note 5).
 
•  In the fourth quarter, we incurred a charge related to Zyprexa product liability litigation matters of $494.9 million (pretax), or $.42 per share (Notes 5 and 14).
 
(CHART)
 
Late-Stage Pipeline Developments and Business Development Activity
 
Our long-term success depends, to a great extent, on our ability to continue to discover and develop innovative pharmaceutical products and acquire or collaborate on compounds currently in development by other biotechnology or pharmaceutical companies. We have achieved a number of successes with late-stage pipeline developments and recent business development transactions within the past year, including:
 
EXECUTIVE
OVERVIEW



 



This section provides an overview of our financial results,
significant business development, recent product and late-stage
pipeline developments, and legal, regulatory, and other matters
affecting our company and the pharmaceutical industry.


 




Financial
Results



 



We achieved worldwide sales growth of 19 percent. This
growth was primarily driven by volume increases in a number of
key products, with a significant portion of this increase in
volume resulting from the acquisition of ICOS. Our additional
investments in marketing and selling expenses in support of key
products, primarily
Cymbalta®

and the diabetes care products, contributed to this sales growth
and enabled us to increase our investment in research and
development 11 percent in 2007. While cost of sales and
operating expenses in the aggregate grew at approximately the
same rate as sales, other income — net decreased and
the effective tax rate increased. As a result, net income and
earnings per share increased 11 percent, to
$2.95 billion, or $2.71 per share, in 2007 as compared with
$2.66 billion, or $2.45 per share, in 2006. Net income
comparisons between 2007 and 2006 are affected by the impact of
the following significant items that are reflected in our
financial results (see Notes 4, 5, and 14 to the
consolidated financial statements for additional information):


 




2007


 
































• 
We recognized asset impairments, restructuring, and other
special charges of $98.2 million (pretax) in the fourth
quarter, which decreased earnings per share by $.07. In the
first quarter, we recognized similar charges associated with
previously announced strategic decisions affecting manufacturing
and research facilities of $123.0 million (pretax), which
decreased earnings per share by $.08 (Note 5).
 
• 
We incurred a special charge following a settlement with one of
our insurance carriers over
Zyprexa®

product liability claims, which led to a reduction of our
expected product liability insurance recoveries. This resulted
in a charge of $81.3 million (pretax), which decreased
earnings per share by $.06 in the third quarter (Notes 5
and 14).
 
• 
We incurred in-process research and development (IPR&D)
charges associated with our licensing arrangement with Glenmark
Pharmaceuticals Limited India of $45.0 million (pretax) and
our licensing arrangement with MacroGenics, Inc., of
$44.0 million (pretax), which decreased earnings per share
by $.05 in the fourth quarter (Note 4).





-17-





Table of Contents





 























• 
We incurred IPR&D charges associated with the acquisition
of Hypnion, Inc. (Hypnion), of $291.1 million (no tax
benefit) and the acquisition of Ivy Animal Health, Inc. (Ivy),
of $37.0 million (pretax), which decreased earnings per
share by $.29 in the second quarter (Note 4).
 
• 
We incurred IPR&D charges associated with the acquisition
of ICOS of $303.5 million (no tax benefit) and a licensing
arrangement with OSI Pharmaceuticals of $25.0 million
(pretax), which decreased earnings per share by $.29 in the
first quarter (Note 4).


 




2006


 























• 
We recognized asset impairments, restructuring, and other
special charges of $450.3 million (pretax) in the fourth
quarter, which decreased earnings per share by $.31
(Note 5).
 
• 
In the fourth quarter, we incurred a charge related to Zyprexa
product liability litigation matters of $494.9 million
(pretax), or $.42 per share (Notes 5 and 14).


 



(CHART)


 




Late-Stage
Pipeline Developments and Business Development
Activity



 



Our long-term success depends, to a great extent, on our ability
to continue to discover and develop innovative pharmaceutical
products and acquire or collaborate on compounds currently in
development by other biotechnology or pharmaceutical companies.
We have achieved a number of successes with late-stage pipeline
developments and recent business development transactions within
the past year, including:


 




These excerpts taken from the LLY 10-K filed Feb 29, 2008.
EXECUTIVE OVERVIEW
 
This section provides an overview of our financial results, significant business development, recent product and late-stage pipeline developments, and legal, regulatory, and other matters affecting our company and the pharmaceutical industry.
 
Financial Results
 
We achieved worldwide sales growth of 19 percent. This growth was primarily driven by volume increases in a number of key products, with a significant portion of this increase in volume resulting from the acquisition of ICOS. Our additional investments in marketing and selling expenses in support of key products, primarily Cymbalta® and the diabetes care products, contributed to this sales growth and enabled us to increase our investment in research and development 11 percent in 2007. While cost of sales and operating expenses in the aggregate grew at approximately the same rate as sales, other income — net decreased and the effective tax rate increased. As a result, net income and earnings per share increased 11 percent, to $2.95 billion, or $2.71 per share, in 2007 as compared with $2.66 billion, or $2.45 per share, in 2006. Net income comparisons between 2007 and 2006 are affected by the impact of the following significant items that are reflected in our financial results (see Notes 3, 4, and 13 to the consolidated financial statements for additional information):
 
2007
 
•  We recognized asset impairments, restructuring, and other special charges of $98.2 million (pretax) in the fourth quarter, which decreased earnings per share by $.07. In the first quarter, we recognized similar charges associated with previously announced strategic decisions affecting manufacturing and research facilities of $123.0 million (pretax), which decreased earnings per share by $.08 (Note 4).
 
•  We incurred a special charge following a settlement with one of our insurance carriers over Zyprexa® product liability claims, which led to a reduction of our expected product liability insurance recoveries. This resulted in a charge of $81.3 million (pretax), which decreased earnings per share by $.06 in the third quarter (Notes 4 and 13).
 
•  We incurred in-process research and development (IPR&D) charges associated with our licensing arrangement with Glenmark Pharmaceuticals Limited India of $45.0 million (pretax) and our licensing arrangement with MacroGenics, Inc., of $44.0 million (pretax), which decreased earnings per share by $.05 in the fourth quarter (Note 3).
 
•  We incurred IPR&D charges associated with the acquisition of Hypnion, Inc. (Hypnion), of $291.1 million (no tax benefit) and the acquisition of Ivy Animal Health, Inc. (Ivy), of $37.0 million (pretax), which decreased earnings per share by $.29 in the second quarter (Note 3).
 
•  We incurred IPR&D charges associated with the acquisition of ICOS of $303.5 million (no tax benefit) and a licensing arrangement with OSI Pharmaceuticals of $25.0 million (pretax), which decreased earnings per share by $.29 in the first quarter (Note 3).
 
2006
 
•  We recognized asset impairments, restructuring, and other special charges of $450.3 million (pretax) in the fourth quarter, which decreased earnings per share by $.31 (Note 4).
 
•  In the fourth quarter, we incurred a charge related to Zyprexa product liability litigation matters of $494.9 million (pretax), or $.42 per share (Notes 4 and 13).


-17-


 

(CHART)
 
Late-Stage Pipeline Developments and Business Development Activity
 
Our long-term success depends, to a great extent, on our ability to continue to discover and develop innovative pharmaceutical products and acquire or collaborate on compounds currently in development by other biotechnology or pharmaceutical companies. We have achieved a number of successes with late-stage pipeline developments and recent business development transactions within the past year, including:
 
EXECUTIVE
OVERVIEW



 



This section provides an overview of our financial results,
significant business development, recent product and late-stage
pipeline developments, and legal, regulatory, and other matters
affecting our company and the pharmaceutical industry.


 




Financial
Results



 



We achieved worldwide sales growth of 19 percent. This
growth was primarily driven by volume increases in a number of
key products, with a significant portion of this increase in
volume resulting from the acquisition of ICOS. Our additional
investments in marketing and selling expenses in support of key
products, primarily
Cymbalta®
and the diabetes care products, contributed to this sales growth
and enabled us to increase our investment in research and
development 11 percent in 2007. While cost of sales and
operating expenses in the aggregate grew at approximately the
same rate as sales, other income — net decreased and
the effective tax rate increased. As a result, net income and
earnings per share increased 11 percent, to
$2.95 billion, or $2.71 per share, in 2007 as compared with
$2.66 billion, or $2.45 per share, in 2006. Net income
comparisons between 2007 and 2006 are affected by the impact of
the following significant items that are reflected in our
financial results (see Notes 3, 4, and 13 to the
consolidated financial statements for additional information):


 




2007


 


















































• 
We recognized asset impairments, restructuring, and other
special charges of $98.2 million (pretax) in the fourth
quarter, which decreased earnings per share by $.07. In the
first quarter, we recognized similar charges associated with
previously announced strategic decisions affecting manufacturing
and research facilities of $123.0 million (pretax), which
decreased earnings per share by $.08 (Note 4).
 
• 
We incurred a special charge following a settlement with one of
our insurance carriers over
Zyprexa®
product liability claims, which led to a reduction of our
expected product liability insurance recoveries. This resulted
in a charge of $81.3 million (pretax), which decreased
earnings per share by $.06 in the third quarter (Notes 4
and 13).
 
• 
We incurred in-process research and development (IPR&D)
charges associated with our licensing arrangement with Glenmark
Pharmaceuticals Limited India of $45.0 million (pretax) and
our licensing arrangement with MacroGenics, Inc., of
$44.0 million (pretax), which decreased earnings per share
by $.05 in the fourth quarter (Note 3).
 
• 
We incurred IPR&D charges associated with the acquisition
of Hypnion, Inc. (Hypnion), of $291.1 million (no tax
benefit) and the acquisition of Ivy Animal Health, Inc. (Ivy),
of $37.0 million (pretax), which decreased earnings per
share by $.29 in the second quarter (Note 3).
 
• 
We incurred IPR&D charges associated with the acquisition
of ICOS of $303.5 million (no tax benefit) and a licensing
arrangement with OSI Pharmaceuticals of $25.0 million
(pretax), which decreased earnings per share by $.29 in the
first quarter (Note 3).


 




2006


 























• 
We recognized asset impairments, restructuring, and other
special charges of $450.3 million (pretax) in the fourth
quarter, which decreased earnings per share by $.31
(Note 4).
 
• 
In the fourth quarter, we incurred a charge related to Zyprexa
product liability litigation matters of $494.9 million
(pretax), or $.42 per share (Notes 4 and 13).





-17-





 






(CHART)


 




Late-Stage
Pipeline Developments and Business Development
Activity



 



Our long-term success depends, to a great extent, on our ability
to continue to discover and develop innovative pharmaceutical
products and acquire or collaborate on compounds currently in
development by other biotechnology or pharmaceutical companies.
We have achieved a number of successes with late-stage pipeline
developments and recent business development transactions within
the past year, including:


 




This excerpt taken from the LLY 10-K filed Feb 28, 2007.
EXECUTIVE OVERVIEW
 
This section provides an overview of our financial results, significant business development, recent product and late-stage pipeline developments, and legal and governmental matters affecting our company and the pharmaceutical industry.
 
Financial Results
 
We achieved worldwide sales growth of 7 percent, primarily as a result of strong growth of our newer products. We increased our investment in marketing expenses in support of key products, primarily Cymbalta® and diabetes care products, and continued our commitment to research and development, investing approximately 20 percent of our sales during 2006. Our results also benefited from continued growth in profitability of the Lilly ICOS joint venture as well as cost-containment and productivity initiatives. Net income was $2.66 billion, or $2.45 per share, in 2006 as compared with $1.98 billion, or $1.81 per share, in 2005, representing an increase in net income and earnings per share of 35 percent. Net income comparisons between 2006 and 2005 are affected by the impact of the following significant items that are reflected in our financial results (see Notes 2, 4, and 13 to the consolidated financial statements for additional information):
 
2006
 
•  We recognized asset impairments, restructuring and other special charges of $450.3 million (pretax) in the fourth quarter, which decreased earnings per share by $.31 (Note 4).
 
•  In the fourth quarter, we incurred a charge related to Zyprexa® product liability litigation matters of $494.9 million (pretax), or $.42 per share (Notes 4 and 13).
 
2005
 
•  We incurred a charge related to product liability litigation matters, primarily related to Zyprexa, of $1.07 billion (pretax), which decreased earnings per share by $.90 in the second quarter of 2005 (Notes 4 and 13).
 
•  We recognized asset impairments and other special charges of $171.9 million (pretax) in the fourth quarter, which decreased earnings per share by $.14 (Note 4).
 
•  We adopted Financial Accounting Standards Board (FASB) Interpretation (FIN) 47, Accounting for Conditional Asset Retirement Obligations, an interpretation of FASB Statement No. 143, in the fourth quarter of 2005. The adoption of FIN 47 resulted in an adjustment for the cumulative effect of a change in accounting principle of $22.0 million (after-tax), which decreased earnings per share by $.02 (Note 2).
 


-16-


 

(GRAPH)
 
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