The Hindu Business Line  Dec 21  Comment 
Glenmark Pharmaceuticals today announced a patent litigation settlement with Forest Laboratories and Royalty Pharma Collection Trust over anti—depressant drug Savella.The company and its US...
newratings.com  Nov 17  Comment 
WASHINGTON (dpa-AFX) - Allergan plc (AGN) announced that it has reached an agreement with the New York State Attorney General's Office to end the litigation and other statutes with the Attorney General over the decision of Forest...
FiercePharma  Nov 10  Comment 
Earlier this year, when a U.S. appeals court officially thwarted Allergan's plan to force patients over to a new, patent-protected version of Namenda before generics hit, it looked like doom for the strategy. But now, Allergan is taking the matter...
The Hindu Business Line  Oct 15  Comment 
Aurobindo Pharma Ltd has received approval from the US Food and Drug Administration (USFDA) to manufacture and market Memantine Hydrochloride tablets used in the treatment of moderate to severe de...
The Hindu Business Line  Oct 14  Comment 
Drug firm Unichem Laboratories has received US health regulator’s approval to market its Memantine Hydrochloride tablets USP, used to treat severe dementia of the Alzheimer’s type, in the American...
FiercePharma  Sep 10  Comment 
After scrambling to convert Namenda patients over to a newer, longer-lasting version of the med, Allergan certainly doesn't want generic competition to the updated version. And for now, it's dodged a bullet, by striking an accord with Amneal to...
FiercePharma  Jul 15  Comment 
Earlier this year, Allergan saw its plans to ease the pain from Namenda generics spoiled by a U.S. appeals court. And now, those generics are here.
The Hindu Business Line  Jul 13  Comment 
Pharma major Dr Reddy’s Laboratories has launched Memantine hydrochloride tablets in the US market following an approval from the United States Food & Drug Administration (USFDA).Th...
newratings.com  Jul 13  Comment 
NEW DELHI (dpa-AFX) - Dr. Reddy's Laboratories (RDY) announced Monday that it has launched Memantine hydrochloride tablets USP, 5 mg and 10 mg, a therapeutic equivalent generic version of NAMENDA (memantine HCl) tablets in the US market on...


Forest Laboratories, Inc. (NYSE: FRX) makes branded and generic prescription drugs. Two drugs account for the majority of Forest's total sales: Lexapro, a drug for the treatment of depression, and Namenda, a drug for the treatment of Alzheimer's disease. The patents for both drugs will expire by 2013., meaning FRX has only a few years to replace the revenue generated by these two products.

New products in Forest Laboratories' pipeline include ceftaroline, an injectable antibiotic acquired through the acquisition of Cerexa, Inc. in 2007; linaclotide, a product for the treatment of gastrointestinal disorders developed through a 50/50 co-development and marketing parntnership with Ironwood Pharmaceuticals, Inc.; and aclidinium, a drug for treating respiratory diseases to which Forest has acquired exclusive United States marketing rights through a collaborative agreement with Laboratorios Almirall SA of Spain.

Three companies make up the majority of FRX's purchasers, making FRX dependent on these major buyers. McKesson (MCK), Cardinal Health (CAH), and AmerisourceBergen Corporation (Holding Co) (ABC) made up 36%, 33%, and 20% of FRX's total sales in 2010 respectively.[1] As a result, the loss of any one customer could have huge implications for FRX's revenues.

Company Overview

Forest Laboratories revenues come primarily from the sales of branded products Lexapro and Namenda, as well as various other branded and generic drugs and several over-the-counter products.

Business and Financial Metrics

FRX has grown its revenues for the past five years. In 2010 (FRX's fiscal year ends March 31 of each year), FRX posted total revenues of $4.19 billion, an increase from its 2009 total revenues of $3.92 billion. However, despite the increase in revenues, FRX's net income actually declined. Between 2009 and 2010, FRX's net income decreased from $768 million in 2009 to $682 million in 2010.[2]

Key Trends and Forces

Forest Laboratories Gets 89% of its Sales From Only Four Drugs

In fiscal 2010, FRX earned 89% of its revenues from four drugs: Lexapro®, Celexa®, Namenda® and Savella®.[3] The patents for both Lexapro and Namenda are set to expire in March 2012, and September, 2013 respectively. If Forest is to remain successful going forward, they will need to develop or license one or more new blockbuster products to make up for the inevitable sales losses to be suffered from the introduction of generics.

The Antidepressant Market is Populated with Numerous Products and Has Begun Slowing

Sales of Lexapro have grown steadily, accounting for 17.7% of total antidepressant prescriptions in the SSRI/SNRI (selective serotonin reuptake inhibitor/serotonin-norepinephrine reuptake inhibitor) category.[4] However, the antidepressant market has slowed, while Lexapro has lost some market share to generics of (ironically enough) Forest Laboratory's own Celexa and other SSRI's.[5]

The Maturation of the Alzheimer's Drug Market Will Slow The Rate of Namenda's Sales Growth

Sales of Forest's Alzheimer's treatment drug Namenda have grown significantly, giving the drug 33.8% of total prescriptions in the Alzheimer's market. This is due largely to its introduction and status as the first FDA approved drug for treatment of moderate-to-late stage Alzheimer's Disease. While Forest Laboratories predicts that sales will continue to grow for the next several years, analysts predict the maturation of the Alzheimer's drug market should continue to slow the rate of growth.


Forest's relatively small size within the pharmaceutical industry makes it particularly susceptible to competition, lacking the financial resources to develop and sell a wide array of products, relying instead on the success of a few key drugs. Some of Forest Laboratories' major competitors include:

  • Teva Pharmaceutical Industries (TEVA): The world's largest producer of generic drugs[6], Teva sells numerous generic versions of the branded drugs that Forest Laboratories produces and sells, most notably Cetalopram, the generic form of Forest's Celexa, a selective serotonin reuptake inhibitor and precursor to Lexapro.[7][8]
  • Pfizer (PFE): One of the worlds largest drug companies with a market cap more than ten times Forest Laboratories',[9] Pfizer develops, produces, and distributes hundreds of pharmaceutical products. These include (most notably from Forest's point of view) three different types of antidepressants (including SSRI Zoloft)[10] and Aricept, a drug for the treatment of Alzheimer's disease[11]
  • Eli Lilly and Company (LLY): Another major pharmaceutical company that develops, produces and distributes drugs including Prozac and Cymbalta for depression.[12] Their status as a producer of central nervous system drugs makes them a direct competitor of Forest's.
Company Total Revenues (most recent filing) R&D Expenditures (most recent filing) Net Income (most recent filing)
Forest Laboratories (FRX)$3.84 B$671 MM$968 MM
Pfizer (PFE)$48.42 B$8.10 B$8.14 B
Eli Lilly and Co (LLY)$18.63 B$3.49 B$2.95 B
Teva Pharmaceuticals (TFE)$2.82 B$198 MM$539 MM


  1. FRX 10-K 2010 Item 1 Pg. 16
  2. FRX 10-K 2010 Item 8 Pg. 46
  3. FRX 10-K 2010 Item 8 Pg. 55
  4. "Forest Laboratories Form 10-K For Fiscal Year 2008; Part IV, Condition and Results of Operations"
  5. The Value Line's Custom Report of Forest Laboratories, 7/2008
  6. "BioJerusalem entry on Teva Pharmaceutical Industries."
  7. "Notes to Consolidated Financial Statements from Forest Laboratories Form 10-K, Section IV"
  8. "Wikipedia entry on Celexa (citalopram)"
  9. "Google Finance's Coverage of Pfizer"
  10. "Pfizer's List of Products for the Treatment of Depression, August 2008"
  11. "Pfizer's List of Products for the Treatment of Alzheimer's Disease, August 2008"
  12. "Eli Lilly's Official Product List, August 2008"
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