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Metabolix to Conduct a Webcast of Its Third Quarter 2009 Earnings Call

Metabolix, Inc. (NASDAQ: MBLX), a bioscience company focused on developing sustainable solutions for plastics, chemicals and energy, announced today that it will be releasing its third quarter 2009 financial results after the close of market on Thursday, October 29, 2009. The full text of the earnings release will also be available on the Company’s website at www.metabolix.com.

Richard Eno, the Company’s President and CEO, and Joseph Hill, CFO, will host a conference call on the same day at 4:30 p.m. EST to discuss the results of the third fiscal quarter, ended September 30, 2009, and to answer questions from the investor audience. To participate, dial toll-free 1-888-430-8701 or 1-719-955-1564 (international) and enter the passcode: 6984164. The conference call will also be webcast and can be accessed from the Company’s website at www.metabolix.com in the investor relations section.

To listen to a telephonic replay of the conference call, dial toll-free 1-888-203-1112 or 1-719-457-0820 (international) and enter the passcode: 6984164. The telephonic replay will be available beginning at 7:30 p.m. EST on Thursday, October 29, 2009, and will last through 11:59 p.m. EST on November 5, 2009. In addition, the webcast will be archived on the Company’s website in the investor relations section.

About Metabolix

Founded in 1992, Metabolix, Inc. is an innovation driven bioscience company focused on providing sustainable solutions for the world’s needs for plastics, chemicals and energy. The Company is taking a systems approach, from gene to end product, integrating sophisticated biotechnology with advanced industrial practice. Metabolix is now developing and commercializing Mirel™, a family of high performance bioplastics which are biobased and biodegradable alternatives to many petroleum-based plastics. Metabolix is also developing a proprietary platform technology for co-producing plastics, chemicals and energy, from crops such as switchgrass, oilseeds and sugarcane.

For more information, please visit www.metabolix.com.

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