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These excerpts taken from the OPTR 10-K filed Mar 12, 2009. Background. Carbohydrates are the most abundant
class of biological molecules in nature and are fundamental to many
physiological processes, which can be inhibited or augmented by
carbohydrate-based drugs. We believe these processes represent potential drug
targets for infectious diseases, cancer and immune-related disorders.
Carbohydrates, however, can be difficult to synthesize because of their complex
molecular structure. Historically, the synthesis of complex carbohydrate
molecules took weeks to months to complete, and thus carbohydrate synthesis for
use in therapeutics has often been characterized as prohibitively difficult and
time-consuming. Numerous drugs currently on the market have carbohydrate
components, which are often implicated in bacterial resistance, and numerous
diseases involve interactions with carbohydrate molecules. Carbohydrate
synthesis involves the manipulation of existing drugs to improve their spectrum
of activity or significantly reduce their side effects. Such drugs include
aminoglycosides, glycopeptides, macrolides and antivirals.
Background. Carbohydrates are the most abundant class of biological molecules in nature and are fundamental to many physiological processes, which can be inhibited or augmented by carbohydrate-based drugs. We believe these processes represent potential drug targets for infectious diseases, cancer and immune-related disorders. Carbohydrates, however, can be difficult to synthesize because of their complex molecular structure. Historically, the synthesis of complex carbohydrate molecules took weeks to months to complete, and thus carbohydrate synthesis for use in therapeutics has often been characterized as prohibitively difficult and time-consuming. Numerous drugs currently on the market have carbohydrate components, which are often implicated in bacterial resistance, and numerous diseases involve interactions with carbohydrate molecules. Carbohydrate synthesis involves the manipulation of existing drugs to improve their spectrum of activity or significantly reduce their side effects. Such drugs include aminoglycosides, glycopeptides, macrolides and antivirals.
These excerpts taken from the OPTR 10-K filed Mar 26, 2008. Background. Carbohydrates are the most abundant class
of biological molecules in nature and are fundamental to many physiological
processes, which can be inhibited or augmented by carbohydrate-based drugs. We
believe these processes represent potential drug targets for infectious
diseases, cancer and immune-related disorders. Carbohydrates, however, can be
difficult to synthesize because of their complex molecular structure. Historically,
the synthesis of complex carbohydrate molecules took weeks to months to
complete, and thus carbohydrate synthesis for use in therapeutics has often
been characterized as prohibitively difficult and time-consuming. Numerous
drugs currently on the market have carbohydrate components, which are often
implicated in bacterial resistance, and numerous diseases involve interactions
with carbohydrate molecules. Carbohydrate synthesis involves the manipulation
of existing drugs to improve their spectrum of activity or significantly reduce
their side effects. Such drugs include aminoglycosides, glycopeptides,
macrolides and antivirals.
13
Background. Carbohydrates are the most abundant class of biological molecules in nature and are fundamental to many physiological processes, which can be inhibited or augmented by carbohydrate-based drugs. We believe these processes represent potential drug targets for infectious diseases, cancer and immune-related disorders. Carbohydrates, however, can be difficult to synthesize because of their complex molecular structure. Historically, the synthesis of complex carbohydrate molecules took weeks to months to complete, and thus carbohydrate synthesis for use in therapeutics has often been characterized as prohibitively difficult and time-consuming. Numerous drugs currently on the market have carbohydrate components, which are often implicated in bacterial resistance, and numerous diseases involve interactions with carbohydrate molecules. Carbohydrate synthesis involves the manipulation of existing drugs to improve their spectrum of activity or significantly reduce their side effects. Such drugs include aminoglycosides, glycopeptides, macrolides and antivirals.
13
This excerpt taken from the OPTR 10-K filed Mar 30, 2007. Background.
Carbohydrates are the most abundant class of biological molecules in
nature and are fundamental to many physiological processes, which can be
inhibited or augmented by carbohydrate-based drugs. We believe these processes represent
potential drug targets for infectious diseases, cancer and immune-related
disorders. Carbohydrates, however, can
be difficult to synthesize because of their complex molecular structure. Historically, the synthesis of complex
carbohydrate molecules took weeks to months to complete, and thus carbohydrate
synthesis for use in therapeutics has often been characterized as prohibitively
difficult and time-consuming. Numerous
drugs currently on the market have carbohydrate components, which are often
implicated in bacterial resistance, and numerous diseases involve interactions
with carbohydrate molecules. Carbohydrate
synthesis involves the
16 manipulation of existing drugs to improve their spectrum of activity or significantly reduce their side effects. Such drugs include aminoglycosides, glycopeptides, macrolides and antivirals. | EXCERPTS ON THIS PAGE:
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