Pharmacopeia Drug Discovery (PCOP)

Stock Ownership of Principal Stockholders and Management

        The following table sets forth the beneficial ownership of our Common Stock as of March 18, 2005 (i) by all persons known to us to be the beneficial owners of more than 5% of our Common Stock, (ii) by each of the executive officers named in the table under "Executive Compensation-Summary Compensation Table," (iii) by each director and nominee for director, and (iv) by all current directors and executive officers as a group. Unless otherwise specified, all shares are directly held.

*

Less than one percent.

(1)

Gives effect to the shares of the Company's Common Stock issuable within 60 days of March 18, 2005 upon the exercise of all options and other rights beneficially owned by the indicated stockholders on that date. Unless otherwise indicated, the persons named in the table have sole voting and sole investment power with respect to all shares shown as being beneficially owned. Beneficial ownership is determined in accordance with the rules of the Securities and Exchange Commission and includes voting and investment power with respect to shares.

(2)

Wellington Management Company, LLP filed an amended Schedule 13G with respect to the Company's Common Stock on February 14, 2005. All data in this Proxy Statement regarding such ownership is based on such amended Schedule 13G. Wellington Management Company, LLP shares voting power with respect to 1,405,799 of the indicated shares, and shares dispositive power with respect to 1,619,999 of the indicated shares.

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(3)

Brown Capital Management, Inc. filed an amended Schedule 13G with respect to the Company's Common Stock on February 9, 2005. All data in this Proxy Statement regarding such ownership is based on such amended Schedule 13G. Brown Capital Management, Inc. has sole voting power with respect to 804,373 of the indicated shares, and sole dispositive power with respect to all of the indicated shares. Brown Capital Management, Inc. does not have shared voting or dispositive power with respect to any of the indicated shares.

(4)

David J. Greene and Company, L.L.C. filed an amended Schedule 13G with respect to the Company's Common Stock on February 4, 2004. All data in this Proxy Statement regarding such ownership is based on such amended Schedule 13G. David J. Greene and Company, L.L.C. has sole voting power with respect to 5,800 of the indicated shares and shares voting power with respect to 1,191,100 of the indicated shares. David J. Greene and Company, L.L.C. has sole dispositive power with respect to 5,800 of the indicated shares and shares dispositive power with respect to 1,946,538 of the indicated shares.

(5)

OZ Management, L.L.C. filed an amended Schedule 13G with respect to the Company's Common Stock on February 14, 2005. All data in this Proxy Statement regarding such ownership is based on such Schedule 13G. OZ Management, L.L.C. has sole voting and dispositive power with respect to all of the indicated shares.

(6)

Includes 391,078 shares of the Company's Common Stock subject to options exercisable within 60 days of March 18, 2005.

(7)

Includes 458,935 shares of the Company's Common Stock subject to options exercisable within 60 days of March 18, 2005.

(8)

Includes 160,227 shares of the Company's Common Stock subject to options exercisable within 60 days of March 18, 2005.

(9)

Includes 35,100 shares of the Company's Common Stock subject to options exercisable within 60 days of March 18, 2005.

(10)

Includes 28,500 shares of the Company's Common Stock subject to options exercisable within 60 days of March 18, 2005.

(11)

Includes 31,799 shares of the Company's Common Stock subject to options exercisable within 60 days of March 18, 2005.

(12)

Includes 28,499 shares of the Company's Common Stock subject to options exercisable within 60 days of March 18, 2005.

(13)

Includes 12,000 shares of the Company's Common Stock subject to options exercisable within 60 days of March 18, 2005.

(14)

Includes 1,146,138 shares of the Company's Common Stock subject to options exercisable within 60 days of March 18, 2005.