newratings.com  Sep 10  Comment 
WASHINGTON (dpa-AFX) - Seattle Genetics Inc (SGEN) and Genmab A/S (GNMSF.PK) on Wednesday entered into an additional antibody-drug conjugate collaboration. Under the new agreement, Genmab will pay an upfront fee of $11 million for exclusive...
SeekingAlpha  Aug 19  Comment 
By Stephen Simpson, CFA: Oncology biotech Seattle Genetics (NASDAQ:SGEN) has had a bit of an interesting ride since I reviewed the company's prospects and valuation back in December. The shares moved up about 40% through February of this year on...
newratings.com  Aug 12  Comment 
WASHINGTON (dpa-AFX) - Seattle Genetics Inc. (SGEN) announced Tuesday that it has initiated a phase 1 clinical trial evaluating SGN-CD70A for CD70-positive relapsed or refractory non-Hodgkin lymphoma or NHL and metastatic renal cell carcinoma or...
Market Intelligence Center  Aug 7  Comment 
Wednesday’s trading in Seattle Genetics Inc. (SGEN) gives options traders an opportunity for a 11.75% return. By selling the Dec. '14 $37.00 call and buying the Jan. '16 call at the $17.50 level for a net debit of $17.45, traders will book a...
newratings.com  Jul 31  Comment 
WASHINGTON (dpa-AFX) - Seattle Genetics Inc. (SGEN) Thursday reported second-quarter net loss of $17.6 million or $0.14 per share, wider than $6.9 million or $0.06 per share last year. Analysts polled by Thomson Reuters estimated a loss of $0.22...
Market Intelligence Center  Jul 25  Comment 
Thursday’s trading in Seattle Genetics Inc. (SGEN) gives options traders an opportunity for a 32.95% return. By selling the Jan. '15 $34.00 call and buying the Jan. '15 call at the $22.50 level for a net debit of $8.65, traders will book a...
TheStreet.com  Jul 16  Comment 
SGEN data by YCharts NEW YORK (TheStreet) -- Seattle Genetics  is having a bipolar year. Significant progress is being made to expand the use of the lymphoma drug Adcetris and on advancing the pipeline, yet the stock price is caught in a...
Benzinga  Jul 9  Comment 
In a research note released Wednesday, UBS analyst Matthew Roden upgraded Seattle Genetics (NASDAQ: SGEN) from Neutral to Buy and maintained a $48.00 price target. Roden said the firm made the upgrade based on two primary reasons: the stock's...
Motley Fool  Jul 1  Comment 
Merck could be gearing up for an acquisition spree. Could Inovio, Seattle Genetics, and MannKind be potential takeover targets?
newratings.com  May 31  Comment 
SOUTH SAN FRANCISCO (dpa-AFX) - Seattle Genetics Inc. (SGEN) announced data from several collaborator antibody-drug conjugate (ADC) programs presented at the American Society of Clinical Oncology (ASCO) 50th Annual Meeting. Seattle Genetics and...


Seattle Genetics, Inc. is a biotechnology company developing monoclonal antibody-based therapies for treating cancer and autoimmune disease.[1] The company is working to develop next generation monoclonal therapies called antibody-drug conjugates (ADCs). The technology links potent synthetic drugs with monoclonal antibodies. The company has collaborations with major industry players all over the world such as: Millennium Pharmaceuticals, Bayer AG (BAYRY), Celldex Therapeutic (BER:TCE1), GlaxoSmithKline (GSK), Genentech (DNA), and quite a few others.[1] Leveraging these collaborations the company is working to navigate the high development costs and regulations that are indicative of the drug industry.

Business Growth

Seattle Genetics does not have any commercial products yet, but had revenue of $107.5 million for 2010. This was an increase of 107% from 2009. The company derived its revenue from payments that included technology access and maintenance fees, milestone and reimbursement payments from its collaborations. Its large jump from 2009 was primarily due to payments received from its collaborations with Genentech, Millennium, and other ADC collaborations.[1]

Trends and Forces

High Costs of Drug Development make it Difficult for Small Companies like Seattle Genetics

For more detailed information on the FDA approval process, see also Clinical trials.

Developing a new drug is a time-consuming and costly endeavor. Hundreds of thousands of candidate compounds must be screened to identify a handful of potential drugs, and even fewer of these candidate drugs are found to be effective at treating a disease. The drug must then pass strict safety standards in several series of clinical trials. The entire process of developing a new drug and bringing it to the market takes up to 10 to 15 years and on average costs $1.3 billion.[2]

Tightening Food and Drug Administration (FDA) Regulations

Beginning in 2009, the FDA implemented a series of reforms that include stricter monitoring of drug adverse events, more funding for the agency, stronger ability to force product recalls, more scientific expertise within the agency, more transparency. Even before 2009 the result has been a much more conservative FDA, demanding more product information.[3]


The various aspects of patent protection and the extremely high costs of researching and developing drugs marks the pharmaceutical industry with high risk and high competitiveness. It is important to keep in mind when considering a comparison of industry players that competition does not arise between each company as a whole, but rather between specific drug areas and their relative advantages in therapeutic treatment. Due to this fact many of Seattle Genetic's collaborators are competitors since they are developing therapies in similar disease areas. They include:


  1. 1.0 1.1 1.2 Seattle Genetics 2010 10k
  2. DiMasi, Joseph, “The Cost of Biopharmaceutical R&D: Is Biotech Different?,” Managerial and Decision Economics, 2007
  3. The FDA: A tough tonic
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