Market Intelligence Center  Aug 27  Comment 
Seattle Genetics Inc. (SGEN) presents a trading opportunity that offers a 8.23% return in just 113 days. A covered call on Seattle Genetics at the $40.00 level expiring on Dec. '15 offers an assigned return rate of 8.23% or 26.57% annualized....
Market Intelligence Center  Aug 21  Comment 
For a hedged play on Seattle Genetics Inc. (SGEN), MarketIntelligenceCenter.com’s option-trade picking algorithms recommend the Dec. '15 $42.00 covered call for a net debit in the $38.51 area. That is also the break-even stock price for the...
FiercePharma  Aug 18  Comment 
Seattle Genetics just won a boost for its lymphoma drug Adcetris. The FDA added a new indication to the drug's toolbox, for patients with Hodgkin's lymphoma at high risk of relapse after a stem-cell transplant.
Benzinga  Aug 18  Comment 
In a report published Tuesday, Piper Jaffray analyst Edward A. Tenthoff maintained an Underweight rating and price target of $30 on Seattle Genetics, Inc. (NASDAQ: SGEN). The company's ADCETRIS candidate has received approval for use in...
newratings.com  Aug 18  Comment 
WASHINGTON (dpa-AFX) - BioLineRx Ltd. (BLRX) has initiated a phase 2b trial for BL-8040 as a novel consolidation treatment for acute myeloid leukemia, and the study will enroll up to 194 patients, randomized in 1:1 ratio, at up to 25 sites in...
Market Intelligence Center  Jul 23  Comment 
After closing Wednesday at $51.02, Seattle Genetics Inc. (SGEN) presents an attractive opportunity to get a 6.79% return in just 57 days, which is an annualized return of 43.49% (for comparison purposes only). To enter this trade, sell one Sep....
Market Intelligence Center  Jun 29  Comment 
After closing Friday at $47.45, Seattle Genetics Inc. (SGEN) presents an attractive opportunity to get a 6.70% return in just 53 days, which is an annualized return of 46.12% (for comparison purposes only). To enter this trade, sell one Aug. '15...


Seattle Genetics, Inc. is a biotechnology company developing monoclonal antibody-based therapies for treating cancer and autoimmune disease.[1] The company is working to develop next generation monoclonal therapies called antibody-drug conjugates (ADCs). The technology links potent synthetic drugs with monoclonal antibodies. The company has collaborations with major industry players all over the world such as: Millennium Pharmaceuticals, Bayer AG (BAYRY), Celldex Therapeutic (BER:TCE1), GlaxoSmithKline (GSK), Genentech (DNA), and quite a few others.[1] Leveraging these collaborations the company is working to navigate the high development costs and regulations that are indicative of the drug industry.

Business Growth

Seattle Genetics does not have any commercial products yet, but had revenue of $107.5 million for 2010. This was an increase of 107% from 2009. The company derived its revenue from payments that included technology access and maintenance fees, milestone and reimbursement payments from its collaborations. Its large jump from 2009 was primarily due to payments received from its collaborations with Genentech, Millennium, and other ADC collaborations.[1]

Trends and Forces

High Costs of Drug Development make it Difficult for Small Companies like Seattle Genetics

For more detailed information on the FDA approval process, see also Clinical trials.

Developing a new drug is a time-consuming and costly endeavor. Hundreds of thousands of candidate compounds must be screened to identify a handful of potential drugs, and even fewer of these candidate drugs are found to be effective at treating a disease. The drug must then pass strict safety standards in several series of clinical trials. The entire process of developing a new drug and bringing it to the market takes up to 10 to 15 years and on average costs $1.3 billion.[2]

Tightening Food and Drug Administration (FDA) Regulations

Beginning in 2009, the FDA implemented a series of reforms that include stricter monitoring of drug adverse events, more funding for the agency, stronger ability to force product recalls, more scientific expertise within the agency, more transparency. Even before 2009 the result has been a much more conservative FDA, demanding more product information.[3]


The various aspects of patent protection and the extremely high costs of researching and developing drugs marks the pharmaceutical industry with high risk and high competitiveness. It is important to keep in mind when considering a comparison of industry players that competition does not arise between each company as a whole, but rather between specific drug areas and their relative advantages in therapeutic treatment. Due to this fact many of Seattle Genetic's collaborators are competitors since they are developing therapies in similar disease areas. They include:


  1. 1.0 1.1 1.2 Seattle Genetics 2010 10k
  2. DiMasi, Joseph, “The Cost of Biopharmaceutical R&D: Is Biotech Different?,” Managerial and Decision Economics, 2007
  3. The FDA: A tough tonic
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