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These excerpts taken from the STEM 10-K filed Mar 16, 2009. Other
Neural Collaborations.
We have established a number of research collaborations to
assess both the in vitro potential of the HuCNS-SC
cells and the effects of transplanting HuCNS-SC cells into
preclinical animal models, including a collaboration with
researchers at the Stanford University School of Medicine to
evaluate our human neural stem cells in animal models
Table of Contents
of stroke. The results of these studies demonstrate the targeted
migration of the cells toward the stroke lesion and
differentiation toward the neuronal lineage. Another study with
researchers at Stanford’s School of Medicine demonstrated
that HuCNS-SC cells labeled with magnetic nanoparticles could
non-invasively track the survival and migration of human cells
within the brain. In addition, we concluded an NIH-funded
collaboration with Dr. George A. Carlson of the McLaughlin
Research Institute to investigate the role of Alzheimer’s
plaques in neuronal cell death in Alzheimer’s disease.
Under the collaboration, Dr. Carson transplanted HuCNS-SC
cells into mouse models of Alzheimer’s disease and the
cells showed robust engraftment in an environment riddled with
Alzheimer’s plaques.
Other Neural Collaborations. We have established a number of research collaborations to assess both the in vitro potential of the HuCNS-SC cells and the effects of transplanting HuCNS-SC cells into preclinical animal models, including a collaboration with researchers at the Stanford University School of Medicine to evaluate our human neural stem cells in animal models
Table of Contentsof stroke. The results of these studies demonstrate the targeted migration of the cells toward the stroke lesion and differentiation toward the neuronal lineage. Another study with researchers at Stanford’s School of Medicine demonstrated that HuCNS-SC cells labeled with magnetic nanoparticles could non-invasively track the survival and migration of human cells within the brain. In addition, we concluded an NIH-funded collaboration with Dr. George A. Carlson of the McLaughlin Research Institute to investigate the role of Alzheimer’s plaques in neuronal cell death in Alzheimer’s disease. Under the collaboration, Dr. Carson transplanted HuCNS-SC cells into mouse models of Alzheimer’s disease and the cells showed robust engraftment in an environment riddled with Alzheimer’s plaques. These excerpts taken from the STEM 10-K filed Mar 14, 2008. Other
Neural Collaborations
We have established a number of research collaborations to
assess both the in vitro potential of the HuCNS-SC
cells and the effects of transplanting HuCNS-SC cells into
preclinical animal models, including a collaboration with
Table of Contents
researchers at the Stanford University School of Medicine to
evaluate our human neural stem cells in animal models of stroke.
The results of these studies demonstrate the targeted migration
of the cells toward the stroke lesion and differentiation toward
the neuronal lineage. Another study with researchers at
Stanford’s School of Medicine demonstrated that HuCNS-SC
cells labeled with magnetic nanoparticles could non-invasively
track the survival and migration of human cells within the
brain. In addition, we concluded an NIH-funded collaboration
with Dr. George A. Carlson of the McLaughlin Research
Institute to investigate the role of Alzheimer’s plaques in
neuronal cell death in Alzheimer’s disease. Under the
collaboration, Dr. Carson transplanted HuCNS-SC cells into
mouse models of Alzheimer’s disease and the cells showed
robust engraftment in an environment riddled with
Alzheimer’s plaques.
Other Neural Collaborations We have established a number of research collaborations to assess both the in vitro potential of the HuCNS-SC cells and the effects of transplanting HuCNS-SC cells into preclinical animal models, including a collaboration with
Table of Contentsresearchers at the Stanford University School of Medicine to evaluate our human neural stem cells in animal models of stroke. The results of these studies demonstrate the targeted migration of the cells toward the stroke lesion and differentiation toward the neuronal lineage. Another study with researchers at Stanford’s School of Medicine demonstrated that HuCNS-SC cells labeled with magnetic nanoparticles could non-invasively track the survival and migration of human cells within the brain. In addition, we concluded an NIH-funded collaboration with Dr. George A. Carlson of the McLaughlin Research Institute to investigate the role of Alzheimer’s plaques in neuronal cell death in Alzheimer’s disease. Under the collaboration, Dr. Carson transplanted HuCNS-SC cells into mouse models of Alzheimer’s disease and the cells showed robust engraftment in an environment riddled with Alzheimer’s plaques. This excerpt taken from the STEM 10-K filed Mar 15, 2007. Other
Neural Collaborations.
We have established a number of research collaborations in the
neural field to assess both the in vitro potential of the
HuCNS-SC and the effects of transplanting HuCNS-SC into
preclinical animal models, including a collaboration with
researchers at the Stanford University School of Medicine to
evaluate our human neural stem cells in animal models of stroke.
Collaborative studies regarding the formation of specific
populations of neurons have also been done with researchers at
The University of Texas Medical Branch and the University of
California, San Diego. In addition, we concluded an
NIH-funded collaboration with Dr. George A. Carlson of the
McLaughlin Research Institute to understand the role of
Alzheimer’s plaques in neuronal cell death in
Alzheimer’s disease. Under the collaboration,
Dr. Carson transplanted HuCNS-SC into mouse models of
Alzheimer’s disease and the cells showed robust engraftment
in an environment riddled with Alzheimer’s plaques. We plan
to analyze the engrafted human cells in the brains of the
transplanted mice.
This excerpt taken from the STEM 10-K filed Mar 16, 2006. Other
Neural Collaborations.
We have established a number of other research collaborations in
the neural field to assess the effects of transplanting HuCNS-SC
into preclinical animal models, including a collaboration with
researchers at the Stanford University School of Medicine
pertaining to the evaluation of our human neural stem cells in
animal models of stroke. Collaborative studies regarding the
formation of specific populations of neurons have also been done
with researchers at The University of Texas Medical Branch and
the University of California, San Diego.
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