TPTX » Topics » Tezampanel and NGX426 AMPA/Kainate Receptor Antagonists

This excerpt taken from the TPTX 8-K filed Sep 28, 2006.

Tezampanel and NGX426
AMPA/Kainate Receptor Antagonists

Tezampanel – parenteral product for migraine

Completed two Phase I studies and five Phase IIa studies

Exposure to date: 205 volunteers and patients

Phase IIb study to begin 4Q 2006

NGX426 – oral prodrug of tezampanel

Initiated Phase I in August 2006

Target indications: migraine and chronic pain

This excerpt taken from the TPTX DEFA14A filed Sep 28, 2006.

Tezampanel and NGX426
AMPA/Kainate Receptor Antagonists

Tezampanel – parenteral product for migraine

Completed two Phase I studies and five Phase IIa studies

Exposure to date: 205 volunteers and patients

Phase IIb study to begin 4Q 2006

NGX426 – oral prodrug of tezampanel

Initiated Phase I in August 2006

Target indications: migraine and chronic pain

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