United Therapeutics (UTHR)

Item 5.02.  Departure of Directors or Principal Officers; Election of Directors; Appointment of Principal Officers.

The press release issued by the Company on August 1, 2006 referenced under Item 2.02 above also announced that Fred T. Hadeed, the Company’s Executive Vice President for Business Development and Chief Financial Officer, will change his duties effective August 10, 2006 to cease to serve as Chief Financial Officer while continuing to serve the Company as Executive Vice President for Business Development.  The Company anticipates amending its employment agreement with Mr. Hadeed in connection with his cessation of service as Chief Financial Officer.  Such revised terms have not yet been determined.  Mr. Hadeed notified the Company of his decision on July 28, 2006.

The press release also announced that Mr. John Ferrari, the Company’s Vice President for Finance and Treasurer, will be promoted to Chief Financial Officer and Treasurer effective August 10, 2006.  Mr. Ferrari, age 51, joined the Company in May 2001 as Controller and has been Vice President for Finance since December 31, 2002 and Treasurer since June 2004.  In connection with Mr. Ferrari’s appointment as Chief Financial Officer, the Company anticipates entering into an employment agreement with Mr. Ferrari, the terms of which have not yet been determined.

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