ZymoGenetics (ZGEN)

17. Notices

Any notice required or desired to be given hereunder shall be in writing and shall be deemed sufficiently given when delivered or when mailed by first class certified or registered mail, postage prepaid, to the party for whom intended at the following address:

To the Company:

CEO

ZymoGenetics, Inc.

1201 Eastlake Avenue East

Seattle, WA 98102

To Executive:

Stephen Zaruby

or to such other address, as to either party, as such party shall from time to time designate by like notice to the other.

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17. Notices

Any notice required or desired to be given hereunder shall be in writing and shall be deemed sufficiently given when delivered or when mailed by first class certified or registered mail, postage prepaid, to the party for whom intended at the following address:

or to such other address, as to either party, as such party shall from time to time designate by like notice to the other.

18.3 Notices

All notices, reports and other communications by BMS or Zymo to the other shall:

(a) be in writing in the English language;

(b) refer specifically to this Agreement; and

(c) be sent by electronic or facsimile transmission for which a confirmation of delivery is obtained or by express courier services providing evidence of delivery,

in each case to the respective address specified below (or to such updated address as may be specified in writing to the other party from time to time).

If to BMS:

Bristol-Myers Squibb Company.

Route 206 & Province Line Road

Princeton, NJ 08543-4000

USA

Attn: Senior Vice President, Strategic Transactions Group

FAX: [    *    ]

With a copy to:

Bristol-Myers Squibb Company.

Route 206 & Province Line Road

Princeton, NJ 08543-4000

USA

Attn: Vice President & Senior Counsel, Business Development

FAX: [    *    ]

If to ZGEN:

ZymoGenetics, Inc.

1201 Eastlake Avenue East

Seattle, WA 98102

USA

Attn: General Counsel

FAX: [    *    ]

If to ZG LLC:

ZymoGenetics, LLC

c/o ZymoGenetics, Inc.

1201 Eastlake Avenue East

Seattle, WA 98102

USA

Attn: General Counsel

FAX: [    *    ]

Such notice, report or other communication will be deemed effective as of the date so delivered either by courier service or by electronic or facsimile transmission.

11.2 Notices

Any notice required or permitted to be given under this Agreement will be in writing in the English language, will specifically refer to this Agreement and will be deemed to have been sufficiently given for all purposes if mailed by first class certified or registered mail, postage prepaid, express delivery service or personally delivered or, if sent by facsimile, electronic transmission is confirmed. Unless otherwise notified in writing, the mailing addresses and fax numbers for notice of the Parties will be as described below.

If to Bayer:

Bayer HealthCare LLC

Cardiology and Hematology Business Unit

800 Dwight Way

Berkeley, CA 94701

Attention: Hans Bishop

Executive Vice President

Fax: 510-705-4233

With a copy to (which shall not constitute notice):

General Counsel

Bayer HealthCare LLC

555 White Plains Road

Tarrytown, NY 10591

Attention: Jeffrey M. Greenman

Fax: 914-366-1784

If to ZGEN:

ZymoGenetics, Inc.

1201 Eastlake Avenue East

Seattle, WA 98102

U.S.A.

Attn: Senior Vice President and General Counsel

FAX: (206) 442-6697

16.4 Notices

All notices, reports and other communications by ZGEN or Serono to the other under this Agreement shall:

(a) be in writing in the English language;

(b) refer specifically to this Agreement; and

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(c) be sent by electronic or facsimile transmission for which a confirmation of delivery is obtained or by express courier services providing evidence of delivery,

in each case to the respective address specified below (or to such updated address as may be specified in writing to the other party from time to time).

If to Serono:

Serono S.A.

c/o Serono International S.A.

15 bis, Chemin des Mines

Case Postale 54

CH-1211 Geneve 20

Switzerland

Attn: General Counsel

FAX: 41-22-739-3070

If to ZGEN:

ZymoGenetics, Inc.

1201 Eastlake Avenue East

Seattle, WA 98102

U.S.A.

Attn: Senior Vice President,

  Intellectual Property and Legal Affairs

FAX: (206) 442-6678

Such notice, report or other communication will be deemed effective as of the date so delivered either by courier service or by electronic or facsimile transmission.