QUOTE AND NEWS
Reuters  5 hrs ago  Comment 
Drugmaker Forest Laboratories received a subpoena earlier this month from U.S. prosecutors requesting documents relating to its small-selling lung disorder product, the Tudorza Pressair inhaler, the company said in a filing.
Wall Street Journal  May 23  Comment 
Forest Laboratories said its veteran chief executive and president, Howard Solomon, will retire at the end of the year, ending his five-decade career with the pharmaceutical company.
Market Intelligence Center  May 23  Comment 
Forest Laboratories Inc. (NYSE: FRX) closed Wednesday's trading session at $37.51. In the past year, the stock has hit a 52-week low of $31.28 and 52-week high of $39.09. Forest Laboratories (FRX) stock has been showing support around $37.01 and...
MedPage Today  May 22  Comment 
(MedPage Today) -- Six weeks of treatment with the antidepressant escitalopram (Lexapro) resulted in a lower rate of mental stress-induced chest pain in patients with stable coronary heart disease, a small randomized study found.
Market Intelligence Center  May 17  Comment 
Forest Laboratories Inc. (NYSE: FRX) closed Thursday's trading session at $38.70. In the past year, the stock has hit a 52-week low of $31.28 and 52-week high of $39.09. Forest Laboratories (FRX) stock has been showing support around $38.43 and...
TheStreet.com  May 10  Comment 
NEW YORK (TheStreet) -- CHANGE IN RATINGS AES downgraded at UBS from Buy to Neutral, UBS said. $14 price target. Valuation call, as the stock is up 24% year-to-date. Boston Scientific upgraded at Wells from Market Perform to Outperform,...
FierceBiotech  May 9  Comment 
With its lead drug poised to begin a Phase IIb study for acute heart failure, Trevena grabbed a $30 million investment from Forest Laboratories, which also picked up an option to snag global rights to the biotech's lead therapy with a deal that...
Stock Blog Hub  May 7  Comment 
Forest Laboratories, Inc. (FRX) and Almirall, S.A. recently announced positive top-line data on their chronic obstructive pulmonary disease (COPD) fixed dose combination candidate, aclidinium bromide (LAMA) and formoterol fumarate (LABA). Two...
Market Intelligence Center  May 7  Comment 
Forest Laboratories Inc. (NYSE: FRX) closed Monday's trading session at $37.20. In the past year, the stock has hit a 52-week low of $31.28 and 52-week high of $38.45. Forest Laboratories (FRX) stock has been showing support around $36.90 and...
Benzinga  May 1  Comment 
Forest Laboratories (NYSE: FRX) and Almirall, S.A. (ALM:MC) today announced positive topline results from AUGMENT COPD, the second six-month pivotal phase III clinical trial evaluating the efficacy and safety of investigational fixed dose...




 

Forest Laboratories, Inc. (NYSE: FRX) makes branded and generic prescription drugs. Two drugs account for the majority of Forest's total sales: Lexapro, a drug for the treatment of depression, and Namenda, a drug for the treatment of Alzheimer's disease. The patents for both drugs will expire by 2013., meaning FRX has only a few years to replace the revenue generated by these two products.

New products in Forest Laboratories' pipeline include ceftaroline, an injectable antibiotic acquired through the acquisition of Cerexa, Inc. in 2007; linaclotide, a product for the treatment of gastrointestinal disorders developed through a 50/50 co-development and marketing parntnership with Ironwood Pharmaceuticals, Inc.; and aclidinium, a drug for treating respiratory diseases to which Forest has acquired exclusive United States marketing rights through a collaborative agreement with Laboratorios Almirall SA of Spain.

Three companies make up the majority of FRX's purchasers, making FRX dependent on these major buyers. McKesson (MCK), Cardinal Health (CAH), and AmerisourceBergen Corporation (Holding Co) (ABC) made up 36%, 33%, and 20% of FRX's total sales in 2010 respectively.[1] As a result, the loss of any one customer could have huge implications for FRX's revenues.

Company Overview

Forest Laboratories revenues come primarily from the sales of branded products Lexapro and Namenda, as well as various other branded and generic drugs and several over-the-counter products.

Business and Financial Metrics

FRX has grown its revenues for the past five years. In 2010 (FRX's fiscal year ends March 31 of each year), FRX posted total revenues of $4.19 billion, an increase from its 2009 total revenues of $3.92 billion. However, despite the increase in revenues, FRX's net income actually declined. Between 2009 and 2010, FRX's net income decreased from $768 million in 2009 to $682 million in 2010.[2]

Key Trends and Forces

Forest Laboratories Gets 89% of its Sales From Only Four Drugs

In fiscal 2010, FRX earned 89% of its revenues from four drugs: Lexapro®, Celexa®, Namenda® and Savella®.[3] The patents for both Lexapro and Namenda are set to expire in March 2012, and September, 2013 respectively. If Forest is to remain successful going forward, they will need to develop or license one or more new blockbuster products to make up for the inevitable sales losses to be suffered from the introduction of generics.

The Antidepressant Market is Populated with Numerous Products and Has Begun Slowing

Sales of Lexapro have grown steadily, accounting for 17.7% of total antidepressant prescriptions in the SSRI/SNRI (selective serotonin reuptake inhibitor/serotonin-norepinephrine reuptake inhibitor) category.[4] However, the antidepressant market has slowed, while Lexapro has lost some market share to generics of (ironically enough) Forest Laboratory's own Celexa and other SSRI's.[5]

The Maturation of the Alzheimer's Drug Market Will Slow The Rate of Namenda's Sales Growth

Sales of Forest's Alzheimer's treatment drug Namenda have grown significantly, giving the drug 33.8% of total prescriptions in the Alzheimer's market. This is due largely to its introduction and status as the first FDA approved drug for treatment of moderate-to-late stage Alzheimer's Disease. While Forest Laboratories predicts that sales will continue to grow for the next several years, analysts predict the maturation of the Alzheimer's drug market should continue to slow the rate of growth.

Competition

Forest's relatively small size within the pharmaceutical industry makes it particularly susceptible to competition, lacking the financial resources to develop and sell a wide array of products, relying instead on the success of a few key drugs. Some of Forest Laboratories' major competitors include:

  • Teva Pharmaceutical Industries (TEVA): The world's largest producer of generic drugs[6], Teva sells numerous generic versions of the branded drugs that Forest Laboratories produces and sells, most notably Cetalopram, the generic form of Forest's Celexa, a selective serotonin reuptake inhibitor and precursor to Lexapro.[7][8]
  • Pfizer (PFE): One of the worlds largest drug companies with a market cap more than ten times Forest Laboratories',[9] Pfizer develops, produces, and distributes hundreds of pharmaceutical products. These include (most notably from Forest's point of view) three different types of antidepressants (including SSRI Zoloft)[10] and Aricept, a drug for the treatment of Alzheimer's disease[11]
  • Eli Lilly and Company (LLY): Another major pharmaceutical company that develops, produces and distributes drugs including Prozac and Cymbalta for depression.[12] Their status as a producer of central nervous system drugs makes them a direct competitor of Forest's.
Company Total Revenues (most recent filing) R&D Expenditures (most recent filing) Net Income (most recent filing)
Forest Laboratories (FRX)$3.84 B$671 MM$968 MM
Pfizer (PFE)$48.42 B$8.10 B$8.14 B
Eli Lilly and Co (LLY)$18.63 B$3.49 B$2.95 B
Teva Pharmaceuticals (TFE)$2.82 B$198 MM$539 MM



References

  1. FRX 10-K 2010 Item 1 Pg. 16
  2. FRX 10-K 2010 Item 8 Pg. 46
  3. FRX 10-K 2010 Item 8 Pg. 55
  4. "Forest Laboratories Form 10-K For Fiscal Year 2008; Part IV, Condition and Results of Operations"
  5. The Value Line's Custom Report of Forest Laboratories, 7/2008
  6. "BioJerusalem entry on Teva Pharmaceutical Industries."
  7. "Notes to Consolidated Financial Statements from Forest Laboratories Form 10-K, Section IV"
  8. "Wikipedia entry on Celexa (citalopram)"
  9. "Google Finance's Coverage of Pfizer"
  10. "Pfizer's List of Products for the Treatment of Depression, August 2008"
  11. "Pfizer's List of Products for the Treatment of Alzheimer's Disease, August 2008"
  12. "Eli Lilly's Official Product List, August 2008"
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